heritability

Book review – The Cheating Cell: How Evolution Helps Us Understand and Treat Cancer

7 -minute read

Fifty years ago, US President Richard Nixon declared a “war on cancer” when he signed the National Cancer Act. Despite fantastic progress on some fronts, overall it is clear that we are not winning this battle. Cancer remains one of the leading causes of human mortality. But what if the tired war-metaphor is getting it all wrong? Brimming with thought-provoking questions, The Cheating Cell looks at cancer through an evolutionary lens and forces the reader to radically reconsider cancer; not as a bug, but as a feature of life.

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Book review – Yellowstone Wolves: Science and Discovery in the World’s First National Park

7-minute read

The reintroduction of wolves to Yellowstone National Park is one of the best-known examples of wildlife conservation. To celebrate its 25th anniversary and summarise the many lessons learned, Yellowstone Wolf Project leaders Douglas W. Smith and Daniel R. Stahler, together with wildlife ecologist Daniel R. MacNulty, bring together research from over 70 colleagues in this large, edited collection. The combination of academic content, excellent photography, guest essays, and an online bonus documentary with interviews make this the go-to reference work for anyone wanting to go beyond the headlines on this reintroduction project.

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Book review – Dance of the Dung Beetles: Their Role in Our Changing World

6-minute read

Having just reviewed The Mosquito, I am continuing the theme of small things running the world. Here is another overlooked insect that literally moves mountains, doing the dirty job that nobody wants to do: the dung beetle. Entomologist Marcus Byrne has teamed up with popular science writer Helen Lunn for Dance of the Dung Beetles, a captivating and charming introduction to their cultural history, their role in the history of biology as a discipline, and some really funky contemporary research.

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Book review – Rates of Evolution: A Quantitative Synthesis

7-minute read

The question of the tempo of evolution cuts right to the heart of evolutionary theory. Emeritus professor in evolutionary biology (and a list of other disciplines) Philip D. Gingerich here takes an empirical stab at quantifying how fast evolution happens, something which has not been done very often. The resulting Rates of Evolution is a technical monograph for an academic audience that contains thought-provoking ideas.

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Book review – Hacking the Code of Life: How Gene Editing Will Rewrite Our Futures

Since being released on the world in 2012, the biotechnological tool CRISPR has been making headlines. Biologists used to rely on the relatively blunt tools of genetic modification, but this new tool is so precise and versatile that they now speak of gene editing instead. For people in a hurry, Nessa Carey here provides a primer on the powers and pitfalls of gene editing. Hacking the Code of Life is accessible to readers without much background in genetics, focusing more on the applications and the questions it raises than the nitty-gritty details of the tool itself.

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Book review – Extended Heredity: A New Understanding of Inheritance and Evolution

In my recent review of She Has Her Mother’s Laugh: The Powers, Perversions, and Potential of Heredity, I mentioned how the concept of heredity has become ever fuzzier the more we have learnt about how traits can be passed to the next generation. We have come from a very gene-centric period in biology, but biologists Russell Bonduriansky and Troy Day are ready to shake up the field. Neither a Lamarckian redux nor an attempt to downplay the importance of genes, this book successfully argues that the time has come to take into account non-genetic forms of heredity. Along the way, they provide a very interesting history lesson on how we got here in the first place.

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Book review – The Epigenetics Revolution: How Modern Biology is Rewriting Our Understanding of Genetics, Disease and Inheritance

After the recently published Lamarck’s Revenge: How Epigenetics Is Revolutionizing Our Understanding of Evolution’s Past and Present left me little the wiser on how epigenetics actually works, I decided to track down a copy of Nessa Carey’s The Epigenetics Revolution. As one of two popular books published around the same time, it seemed like a good place to start. Peter Ward was right about one thing, this is indeed a landmark book, even if it is now a few years old.

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Book review – Lamarck’s Revenge: How Epigenetics Is Revolutionizing Our Understanding of Evolution’s Past and Present

As one of several intellectuals who wrote about evolution before Darwin, time has not been kind to the French naturalist Jean-Baptiste Lamarck (1744-1829). Reviled during his lifetime by the influential Cuvier, after his death he became best remembered, and ultimately ridiculed, for the idea that characters acquired during an organism’s lifetime are passed on to its offspring. With the rise of the modern field of epigenetics, some of his ideas are making a comeback, albeit modified and adapted for the 21st Century. Palaeontologist and astrobiologist Peter Ward would even like to go so far as to restore some honour to his name and consider epigenetics a neo-Lamarckian process.

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Book review – Ancestors in Our Genome: The New Science of Human Evolution

After I read and reviewed Who We Are and How We Got Here: Ancient DNA and the New Science of the Human Past, I thought I knew about the changes to the story of human evolution based on studies of DNA. And given that Ancestors in Our Genome was published a few years before that book, I was curious what it could add to what I had been reading so far. As it turns out, a lot. As with my previous review, I should preface this one with the same warning that things are about to get complicated…

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Book review – Blueprint: How DNA Makes Us Who We Are

When I opened this book and read its sales pitch (I paraphrase: “What if I told you of a new fortune-telling device that can predict psychological traits – it’s called the DNA revolution!”) I raised my inquisitive but sceptical eyebrow somewhat. Did I just pick up another piece of pop-psychology pulp? Oh boy, was I wrong! Behavioural geneticist Robert Plomin has written an incredibly interesting book with Blueprint, explaining how rapid advances in DNA sequencing technology are opening vast new vistas on the genetics underlying psychology. And is it ever so different, and more complex, than what hyped-up newspaper headlines have tried to sell us so far.

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