apoptosis

Book review – The Evolutionary Origins of Life and Death

9-minute read
keywords: abiogenesis, cell biology, evolutionary biology

In this second foray into the biology of death, I will examine programmed cell death or PCD. You might have heard of the process of apoptosis, but, as the previously reviewed The Biology of Death mentioned, this is just one of many ways in which cells can actively kill themselves. It is a vital part of life in multicellular organisms, for instance sculpting our hands so that we are not born with webs of skin between our fingers, or allowing leaves to fall from the trees in autumn by triggering cell death in so-called abscission zones. These are small sacrifices to serve the larger organism. Surprisingly, single-celled (unicellular) organisms also show PCD. But wait, is that not tantamount to suicide? How did that evolve?

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Book review – The Cheating Cell: How Evolution Helps Us Understand and Treat Cancer

7 -minute read

Fifty years ago, US President Richard Nixon declared a “war on cancer” when he signed the National Cancer Act. Despite fantastic progress on some fronts, overall it is clear that we are not winning this battle. Cancer remains one of the leading causes of human mortality. But what if the tired war-metaphor is getting it all wrong? Brimming with thought-provoking questions, The Cheating Cell looks at cancer through an evolutionary lens and forces the reader to radically reconsider cancer; not as a bug, but as a feature of life.

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